Deschaux P, Fontanges R
Ann Endocrinol (Paris). 1978;39(1):23-40.
We have studied the interrelation between the thymus and the hypophyso-adrenal and hypophyso-testicular axes in male rats. In the first part of our work, we have essayed the plasma levels of testosterone, LH, corticosterone and ACTH in neonatally thymectomized or thymectomized and hypophysectomized animals. The results obtained allow us to conclude that there is an indirect action (via hypophysis) of the thymus on the testes and a direct action on the adrenals by the intermediary of one active extract. In the second part of our study we measured hormonal activity of the thymus in hypophysectomized or adrenalectomized or orchidectomized rats. The results obtained show that there is no effect of the testes on the thymus secretion; on the other hand the thymus is under the control of hypophysis and adrenals.
我们研究了雄性大鼠胸腺与垂体-肾上腺轴及垂体-睾丸轴之间的相互关系。在我们工作的第一部分,我们测定了新生期胸腺切除或胸腺切除并垂体切除的动物体内睾酮、促黄体生成素、皮质酮和促肾上腺皮质激素的血浆水平。所获得的结果使我们得出结论:胸腺对睾丸有间接作用(通过垂体),并通过一种活性提取物对肾上腺有直接作用。在我们研究的第二部分,我们测定了垂体切除、肾上腺切除或睾丸切除大鼠胸腺的激素活性。所获得的结果表明,睾丸对胸腺分泌没有影响;另一方面,胸腺受垂体和肾上腺的控制。