Mahadeva V, Husted R F
Can J Physiol Pharmacol. 1983 Sep;61(9):1081-4. doi: 10.1139/y83-161.
The Cl-HCO3 exchange rate across turtle urinary bladder was studied by measuring the net flux of 36Cl in paired tissues. Serosal bicarbonate concentration and pH were held constant (10 mM and 7.6, respectively) while luminal composition was altered. The rate of net chloride absorption was the same at a luminal pH of 5 or 7 and at luminal HCO-3 concentrations of 0 and 10 mM. These results indicate that the affinity of the exchanger for luminal Cl- is much higher than that for luminal HCO-3 or OH-. Vanadate, an inhibitor of a number of ATPases, had no significant effect on chloride absorption.
通过测量成对组织中(^{36}Cl)的净通量，研究了龟膀胱跨膜的(Cl-HCO_3)交换率。浆膜碳酸氢盐浓度和pH保持恒定（分别为10 mM和7.6），同时改变管腔成分。在管腔pH为5或7以及管腔(HCO_3^-)浓度为0和10 mM时，净氯吸收速率相同。这些结果表明，该交换体对管腔(Cl^-)的亲和力远高于对管腔(HCO_3^-)或(OH^-)的亲和力。钒酸盐是多种ATP酶的抑制剂，对氯吸收没有显著影响。
