Brodsky W A, Durham J H, Ehrenspeck G
Ann N Y Acad Sci. 1980;341:210-24. doi: 10.1111/j.1749-6632.1980.tb47173.x.
Although the electrogenicity of the active reabsorption of sodium and bicarbonate (or secretion of protons) has been well-established in the short-circuited turtle bladder preparation, the nature of the active reabsorption of chloride and secretion of bicarbonate has been controversial. These processes have been ascribed to the separate actions of two discrete electrogenic pumps or to the single action of a metabolically driven electroneutral anion exchange mechanism. The present report deals with these transport processes per se; with the relations among serosal bicarbonate,glucose, and the reabsorption of Na and Cl; and finally with the application of the Heinz model for inversion of an active transport as a tentative single mechanism for the alkalinization and acidification of the urine.
尽管在短路龟膀胱制备中，钠和碳酸氢盐的主动重吸收（或质子分泌）的电生性已得到充分证实，但氯的主动重吸收和碳酸氢盐的分泌的本质一直存在争议。这些过程被归因于两种离散的电生泵的单独作用，或代谢驱动的电中性阴离子交换机制的单一作用。本报告涉及这些转运过程本身；涉及浆膜碳酸氢盐、葡萄糖与钠和氯重吸收之间的关系；最后涉及应用海因茨模型将主动转运反转作为尿液碱化和酸化的一种暂定单一机制。
