Colla G, Carrea M, Sbaffi A
Ric Clin Lab. 1983 Oct-Dec;13(4):443-8.
A new case of Fletcher factor (prekallikrein) deficiency is described. The patient did not have any abnormal bleeding tendency, but showed defective intrinsic thromboplastin production and reduced fibrinolytic system activity; he had no factor VIII, IX, XI and XII deficiencies. His plasma did not contain any detectable prekallikrein levels.
本文描述了一例新的弗莱彻因子(前激肽释放酶)缺乏症病例。该患者没有任何异常出血倾向,但表现出内源性凝血活酶生成缺陷和纤溶系统活性降低;他不存在因子VIII、IX、XI和XII缺乏。其血浆中未检测到任何前激肽释放酶水平。