Orehek J, Saraga E, Gayrard P, Grimaud C, Charpin J
Nouv Presse Med. 1975 Nov 15;4(39):2789-92.
Frequency of exercise-induced asthma has been studied in 75 unselected asthmatic patients (adults and children) by measuring the forced expiratory volume at one second (FEV1) and the vital capacity (VC) before and after a treadmill exercise, continued until heart rate was at least equal to 80 p.cent-85 p.cent of maximum heart rate. In 19 subjects (25 p.cent), a more than 20 p.cent decrease from control value of FEV1 was recorded ten minutes after exercise ended. Exercise-induced bronchial obstruction was relieved by a beta adrenergic bronchodilator aerosol inhalation. In the group of 19 subjects having exercise-induced asthma, a significant positive correlation was found between pre-exercise FEV1 values and post-exercise FEV1 decreases. In the whole group of 75 subjects exercise-induced asthma was related to the severity of asthma and not to other clinical or physical characteristics of the subjects. From the data of other authors it appears that frequency of exercise-induced asthma is variable. The reasons of those differences are discussed.
通过测量75名未经挑选的哮喘患者（成人和儿童）在跑步机运动前后的一秒用力呼气量（FEV1）和肺活量（VC），研究了运动诱发性哮喘的发生率。运动持续至心率至少等于最大心率的80%-85%。在19名受试者（25%）中，运动结束十分钟后，FEV1较对照值下降超过20%。β肾上腺素能支气管扩张剂气雾剂吸入可缓解运动诱发的支气管阻塞。在19名患有运动诱发性哮喘的受试者组中，运动前FEV1值与运动后FEV1下降之间存在显著正相关。在75名受试者的整个组中，运动诱发性哮喘与哮喘的严重程度有关，而与受试者的其他临床或身体特征无关。从其他作者的数据来看，运动诱发性哮喘的发生率是可变的。讨论了这些差异的原因。
