Balldin U, Linér M
Aviat Space Environ Med. 1978 Jun;49(6):759-62.
The effect of terbutaline on the occurrence of decompression sickness was studied in seven rabbits. Terbutaline is a vasodilator, a sympathomimetic beta2-receptor stimulator. The rabbits were given a hyperbaric exposition at 2 ATA followed by oxygen breathing at 1 ATA and a hypobaric exposition at 0.2 ATA. Each rabbit got a hyperbaric exposition long enough for symptoms of decompression sickness to occur at the hypobaric exposition. With a time interval of at least 1 week, each rabbit received an identical pressure exposition, except that terbutaline was injected intravenously at the beginning of the denitrogenation period at 1 ATA. Of the seven experiments with the drug, only one case of decompression sickness occurred and with a delayed appearance. This may be compared to rapid-appearing decompression sickness in all cases in the control series. The results may be of importance in diving routines and, possibly, in the treatment of decompression sickness.
在七只兔子身上研究了特布他林对减压病发生的影响。特布他林是一种血管扩张剂，一种拟交感神经β2受体刺激剂。兔子先在2个绝对大气压下进行高压暴露，然后在1个绝对大气压下呼吸氧气，再在0.2个绝对大气压下进行低压暴露。每只兔子的高压暴露时间足够长，以便在低压暴露时出现减压病症状。每隔至少1周，每只兔子接受相同的压力暴露，但在1个绝对大气压的排氮期开始时静脉注射特布他林。在使用该药物的七次实验中，仅出现一例减压病，且出现延迟。这可与对照组所有病例中迅速出现的减压病进行比较。该结果可能对潜水程序以及减压病的治疗具有重要意义。
