Effects of 1,1'-oxydimethylene bis-(4-tert-butylpyridinium chloride) (SAD-128) and decamethonium on reactivation of soman- and sarin-inhibited cholinesterase by oximes.

Suppr

超能文献

作者信息

Harris L W, Heyl W C, Stitcher D L, Broomfield C A

出版信息

Biochem Pharmacol. 1978 Mar 1;27(5):757-61. doi: 10.1016/0006-2952(78)90516-6.

DOI:10.1016/0006-2952(78)90516-6

PMID:656114

Abstract

摘要

相似文献

Effects of 1,1'-oxydimethylene bis-(4-tert-butylpyridinium chloride) (SAD-128) and decamethonium on reactivation of soman- and sarin-inhibited cholinesterase by oximes.

Biochem Pharmacol. 1978 Mar 1;27(5):757-61. doi: 10.1016/0006-2952(78)90516-6.

Reactivation of acetylcholinesterase inhibited by 1,2,2'-trimethylpropyl methylphosphonofluoridate (soman) with HI-6 and related oximes.

Biochem Pharmacol. 1980 Sep 1;29(17):2379-87. doi: 10.1016/0006-2952(80)90273-7.

Reactivation of Sarin- or Soman-phosphonylated human acetylcholinesterase by bis-pyridinium mono-oximes.

Biochem Pharmacol. 1986 Jan 15;35(2):347-9. doi: 10.1016/0006-2952(86)90537-x.

Reactivators of organophosphate-inhibited cholinesterase. 4-cycloalkylcarbonyl substituted bis-pyridinium monooximes.

Arch Toxicol. 1984 Sep;55(3):199-202. doi: 10.1007/BF00316129.

Stereospecific reactivation of human brain and erythrocyte acetylcholinesterase inhibited by 1,2,2-trimethylpropyl methylphosphonofluoridate (soman).被1,2,2-三甲基丙基甲基磷酰氟（梭曼）抑制的人脑和红细胞乙酰胆碱酯酶的立体特异性复活

Biochim Biophys Acta. 1985 Aug 23;830(3):345-8. doi: 10.1016/0167-4838(85)90294-8.

HI-6: reactivation of central and peripheral acetylcholinesterase following inhibition by soman, sarin and tabun in vivo in the rat.HI-6：大鼠体内梭曼、沙林和塔崩抑制后中枢和外周乙酰胆碱酯酶的重新激活

Biochem Pharmacol. 1982 Apr 1;31(7):1283-7. doi: 10.1016/0006-2952(82)90017-x.

[Phosphonyloxime of soman; formation and reaction with acetylcholinesterase in vitro].[梭曼的磷酰肟；体外形成及其与乙酰胆碱酯酶的反应]

Biochem Pharmacol. 1973 Dec 1;22(23):2997-3003. doi: 10.1016/0006-2952(73)90186-x.

Reactivators of organophosphate-inhibited cholinesterase. Phenylhydroxymethyl and cyclohexylhydroxymethyl substituted bis-pyridinium monooximes.

Arch Toxicol. 1982 Mar;49(3-4):285-91. doi: 10.1007/BF00347876.

Acceleration of oxime-induced reactivation of organophosphate-inhibited fetal bovine serum acetylcholinesterase by monoquaternary and bisquaternary ligands.单季铵盐和双季铵盐配体对肟诱导的有机磷酸酯抑制的胎牛血清乙酰胆碱酯酶再活化的促进作用。

Mol Pharmacol. 1998 Apr;53(4):718-26. doi: 10.1124/mol.53.4.718.

Synthesis and in vitro kinetic study of novel mono-pyridinium oximes as reactivators of organophosphorus (OP) inhibited human acetylcholinesterase (hAChE).新型单吡啶𬭩肟类化合物的合成及其对有机磷（OP）抑制的人乙酰胆碱酯酶（hAChE）的体外动力学研究。

Chem Biol Interact. 2015 Jul 25;237:125-32. doi: 10.1016/j.cbi.2015.06.007. Epub 2015 Jun 10.

引用本文的文献

Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings.新型双季铵胆碱酯酶抑制剂作为神经毒剂中毒预处理药物的研发。

Drug Des Devel Ther. 2018 Mar 9;12:505-512. doi: 10.2147/DDDT.S133038. eCollection 2018.

Methantheline improves the reactivation by HI 6 of human erythrocyte acetylcholinesterase inhibited by soman in vitro.甲胺太林可提高体外梭曼抑制的人红细胞乙酰胆碱酯酶被HI 6重新激活的能力。

Arch Toxicol. 1995;70(1):16-9. doi: 10.1007/s002040050243.

Multiple binding sites involved in the effect of choline esters on decarbamoylation of monomethylcarbamoyl- or dimethylcarbamoly-acetylcholinesterase.胆碱酯对单甲基氨基甲酰基或二甲基氨基甲酰基乙酰胆碱酯酶脱氨基甲酰作用的效应涉及多个结合位点。

Biochem J. 1994 Aug 1;301 ( Pt 3)(Pt 3):713-20. doi: 10.1042/bj3010713.

In vitro oxime-induced reactivation of various molecular forms of soman-inhibited acetylcholinesterase in striated muscle from rat, monkey and human.体外肟诱导大鼠、猴和人横纹肌中梭曼抑制的不同分子形式乙酰胆碱酯酶的重新激活。

Arch Toxicol. 1994;68(10):648-55. doi: 10.1007/BF03208345.

Mechanism of action of HI-6 on soman inhibition of acetylcholinesterase in preparations of rat and human skeletal muscle; comparison to SAD-128 and PAM-2.HI-6对梭曼抑制大鼠和人骨骼肌制剂中乙酰胆碱酯酶的作用机制；与SAD-128和PAM-2的比较。

Arch Toxicol. 1989;63(1):68-71. doi: 10.1007/BF00334637.

Potentiation effect of choline esters on choline-catalysed decarbamoylation of dimethylcarbamoyl-acetylcholinesterase.胆碱酯对胆碱催化的二甲基氨基甲酰基乙酰胆碱酯酶脱氨基甲酰化的增强作用。

Biochem J. 1992 May 15;284 ( Pt 1)(Pt 1):153-60. doi: 10.1042/bj2840153.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验