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The role of substrate lipophilicity in determining type 1 microsomal P450 binding characteristics.

作者信息

Al-Gailany K A, Houston J B, Bridges J W

出版信息

Biochem Pharmacol. 1978 Mar 1;27(5):783-8. doi: 10.1016/0006-2952(78)90521-x.

DOI:10.1016/0006-2952(78)90521-x
PMID:656117
Abstract
摘要

相似文献

1
The role of substrate lipophilicity in determining type 1 microsomal P450 binding characteristics.
Biochem Pharmacol. 1978 Mar 1;27(5):783-8. doi: 10.1016/0006-2952(78)90521-x.
2
Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene.乙氧芴羟香豆素：一种微粒体O-脱烷基化反应的直接荧光测定法，该反应优先被3-甲基胆蒽诱导。
Drug Metab Dispos. 1974 Nov-Dec;2(6):583-8.
3
Strain differences in the induction of soluble and microsomal enzymes by phenobarbital and 3-methylcholanthrene.苯巴比妥和3-甲基胆蒽对可溶性酶和微粒体酶诱导作用的品系差异。
Chem Biol Interact. 1974 May;8(5):297-302. doi: 10.1016/0009-2797(74)90008-8.
4
Effect of riboflavin deficiency on phenobarbital and 3-methylcholanthrene induction of microsomal drug-metabolizing enzymes of the rat.核黄素缺乏对大鼠微粒体药物代谢酶的苯巴比妥和3-甲基胆蒽诱导作用的影响。
Biochem Pharmacol. 1973 Oct 1;22(19):2365-73. doi: 10.1016/0006-2952(73)90338-9.
5
The utility of the microsomal 4-chlorobiphenyl hydroxylase enzyme assay in distinguishing between phenobarbitone- and 3-methylcholanthrene-induced microsomal monooxygenases.
Anal Biochem. 1980 Jun;105(1):65-73. doi: 10.1016/0003-2697(80)90424-8.
6
[A substrate-type induction of liver microsomal monooxygenases by phenobarbital].[苯巴比妥对肝脏微粒体单加氧酶的底物型诱导作用]
Biokhimiia. 1977 Jul;42(7):1184-94.
7
Allylisopropylacetamide preferentially interacts with the phenobarbital-inducible form of rat hepatic microsomal P-450.
Biochem Pharmacol. 1976 Nov 1;25(21):2415-7. doi: 10.1016/0006-2952(76)90042-3.
8
Effect of phenobarbital and 3-methylcholanthrene administration in vivo and isooctane extraction in vitro on metyrapone binding to reduced cytochrome P-450.
Biochem Pharmacol. 1974 Aug 15;23(16):2305-14. doi: 10.1016/0006-2952(74)90559-0.
9
A highly sensitive radiometric assay for zoxazolamine hydroxylation by liver microsomal cytochrome P-450 and P-448: properties of the membrane-bound and purified reconstituted system.一种用于检测肝微粒体细胞色素P - 450和P - 448催化唑恶苯胺羟基化反应的高灵敏度放射性测定法：膜结合系统和纯化重组系统的特性
Arch Biochem Biophys. 1976 Oct;176(2):788-98. doi: 10.1016/0003-9861(76)90223-x.
10
Interaction of isosafrole in vivo with rat hepatic microsomal cytochrome P-450 following treatment with phenobarbitone or 20-methylcholanthrene.苯巴比妥或20-甲基胆蒽处理后异黄樟素在体内与大鼠肝微粒体细胞色素P-450的相互作用。
Biochem Pharmacol. 1979 Apr 15;28(8):1427-9. doi: 10.1016/0006-2952(79)90447-7.

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Biochem J. 2002 Mar 15;362(Pt 3):545-51. doi: 10.1042/0264-6021:3620545.
5
Structural parameters in the microsomal hydrolysis of 3-acyloxy-1, 4-benzodiazepines and the multiplicity of the esterases involved.3-酰氧基-1,4-苯二氮䓬微粒体水解中的结构参数及相关酯酶的多样性。
Eur J Drug Metab Pharmacokinet. 1980;5(4):193-200. doi: 10.1007/BF03189464.
6
Interaction of 7-n-alkoxycoumarins with cytochrome P-450(2) and their partitioning into liposomal membranes. Assessment of methods for determination of membrane partition coefficients.7-正烷氧基香豆素与细胞色素P-450(2)的相互作用及其在脂质体膜中的分配。膜分配系数测定方法的评估。
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