Krizhevskaia Iu V, Gomazkov O A, Ionov B V, Denisova M N
Biull Eksp Biol Med. 1984 Aug;98(8):131-4.
The importance of the platelet count and intactness for contact Hageman's factor-dependent activation of blood plasma kallikrein has been demonstrated. The degree of kallikrein activation was in agreement with the count of platelets contained by the sample. Kallikrein activation was also found to be potentiated by the membrane fraction of washed platelets and of those destroyed by freezing and thawing. The cellular contents did not produce any significant effect on the activation in question.
血小板计数和完整性对接触性激活血浆激肽释放酶依赖的哈格曼因子的重要性已得到证实。激肽释放酶的激活程度与样品中的血小板计数一致。还发现,洗涤血小板以及经冻融破坏的血小板的膜部分可增强激肽释放酶的激活。细胞内容物对所述激活没有任何显著影响。