Avtandilov G T, Tsibel' B N
Biull Eksp Biol Med. 1978 May;85(5):613-5.
A microspectrophotometric study of sialomucins in human glomerular filter of the kidney in some diseases was carried out. Sialomucins were detected in paraffine sections stained after Haim, and examined on scanning microspectrophotometer. Lipid nephrosis, secondary amyloidosis, membranous-proliferative glomerulonephritis with the nephrotic syndrome were accompanied by a significant decrease in the amount of sialic acid. No reduction of sialomucins occurred in subacute glomerulonephritis with the nephrotic syndrome. A connection between the selective proteinuria and a decrease of the amount of sialomucins in the glomerulus is suggested.
对某些疾病患者肾脏的人肾小球滤过器中的涎粘蛋白进行了显微分光光度研究。在经海姆染色后的石蜡切片中检测到涎粘蛋白，并在扫描显微分光光度计上进行检查。脂性肾病、继发性淀粉样变性、伴有肾病综合征的膜增生性肾小球肾炎患者的唾液酸含量显著降低。伴有肾病综合征的亚急性肾小球肾炎患者的涎粘蛋白没有减少。提示肾小球中选择性蛋白尿与涎粘蛋白量减少之间存在联系。
