Kucera H, Skodler W, Weghaupt K
Geburtshilfe Frauenheilkd. 1984 Aug;44(8):498-502. doi: 10.1055/s-2008-1036704.
A report is given about reversible and irreversible complications following postoperative irradiation in cases of endometrial carcinomas. Intravaginal brachytherapy (Ra226, vaginal cylinder applicator) is given. In advanced cases or in cases with poor prognosis (tumor grading) percutaneous irradiation was added (Co60). Reversible complications (cystitis, proctitis) could be observed in 7%, irreversible complications (fistulas, stenosis) in 1.9% of the cases, respectively. The rate of radiation side effects after primary operation is lower than after primary irradiation of endometrial carcinoma. This is contrary to the results in postoperative irradiation of cervical carcinoma with a markedly higher rate of irradiation side effects. After postoperative intravaginal brachytherapy (Ra226) alone, only in 5.9% of the cases reversible and in 0.8% irreversible complications were observed.
本文给出了子宫内膜癌术后放疗后可逆性和不可逆性并发症的报告。采用阴道内近距离放疗(镭226,阴道柱状施源器)。对于晚期病例或预后较差(肿瘤分级)的病例,加用经皮放疗(钴60)。分别有7%的病例出现可逆性并发症(膀胱炎、直肠炎),1.9%的病例出现不可逆性并发症(瘘管、狭窄)。初次手术后放疗的副作用发生率低于子宫内膜癌初次放疗后的发生率。这与宫颈癌术后放疗的结果相反,宫颈癌术后放疗的副作用发生率明显更高。仅行术后阴道内近距离放疗(镭226)时,仅5.9%的病例出现可逆性并发症,0.8%的病例出现不可逆性并发症。