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大鼠晶状体的出生后早期发育

Early postnatal development of the rat lens.

作者信息

Sivak J G, Dovrat A

出版信息

Exp Biol. 1984;43(1):57-65.

PMID:6570670
Abstract

Late prenatal and early postnatal development of the human crystalline lens is described as a process of continued flattening brought on by equatorial mitotic activity. The rat lens is relatively flat at birth, the difference between the axial and equatorial diameters being approximately equal to those of the lens of a newborn human. However, the rat lens rapidly becomes more spherical in shape after birth, with the lens occupying most of the intraocular space, as in adults, by 16 days. Study of the optical quality of excised lenses, from photographs of lens refractive effects on parallel laser beams of varying separation, indicates that the lens of the newborn rat is relatively free of the large negative spherical aberration found in adult lenses. However, large amounts of negative spherical aberration are evident five days after birth. It is suggested that the refractive components of the rat eye are similar in appearance and quality to those of a diurnal mammal at birth and that they assume the characteristics associated with nocturnal vision during an early period of postnatal development.

摘要

人类晶状体的产前晚期和产后早期发育被描述为一个由赤道有丝分裂活动导致持续变平的过程。大鼠晶状体在出生时相对扁平,其轴径和赤道径之差与新生儿晶状体的相应差值大致相等。然而,大鼠晶状体在出生后迅速变得更呈球形,到16天时,晶状体占据了眼内的大部分空间,如同成年大鼠一样。通过拍摄不同间距的平行激光束经晶状体折射后的照片来研究摘除晶状体的光学质量,结果表明新生大鼠的晶状体相对没有成年晶状体中存在的大的负球差。然而,出生五天后明显出现大量负球差。有人提出,大鼠眼睛的屈光成分在出生时在外观和质量上与昼行性哺乳动物的相似,并且在出生后的早期发育阶段呈现出与夜行性视觉相关的特征。

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Early postnatal development of the rat lens.大鼠晶状体的出生后早期发育
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Aging and the optical quality of the rat crystalline lens.衰老与大鼠晶状体的光学质量
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