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衰老与大鼠晶状体的光学质量

Aging and the optical quality of the rat crystalline lens.

作者信息

Sivak J G, Dovrat A

出版信息

Invest Ophthalmol Vis Sci. 1983 Sep;24(9):1162-6.

PMID:6885305
Abstract

Split laser beams of varying separation were directed through the crystalline lenses of rats of young, old, and intermediate age. The variation in back vertex distance was determined from photographs of the focal effects of each lens. The results indicate that negative spherical aberration of the rat lens increases with age. In addition, local reversals in the slopes of the negative spherical aberration curves are larger and more frequent in the older lenses. The increase in negative spherical aberration is likely due to tighter packing of central lens fibers and a consequent increase in central refractive index although change in lens shape may contribute as well.

摘要

将不同间距的分束激光束穿过幼年、老年和中年大鼠的晶状体。根据每个晶状体聚焦效果的照片确定后顶点距离的变化。结果表明,大鼠晶状体的负球差随年龄增长而增加。此外,老年晶状体中负球差曲线斜率的局部反转更大且更频繁。负球差的增加可能是由于晶状体中央纤维的紧密堆积以及随之而来的中央折射率增加,尽管晶状体形状的变化也可能起一定作用。

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