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原住民社区急性链球菌感染后肾小球肾炎的流行情况。

Epidemic of acute poststreptococcal glomerulonephritis in aboriginal communities.

作者信息

Gogna N K, Nossar V, Walker A C

出版信息

Med J Aust. 1983 Jan 22;1(2):64-6. doi: 10.5694/j.1326-5377.1983.tb136039.x.

DOI:10.5694/j.1326-5377.1983.tb136039.x
PMID:6571580
Abstract

During 1980, an epidemic of acute glomerulonephritis occurred in a number of Aboriginal communities in the Northern Territory, affecting several hundred people. Clinical and laboratory studies of children admitted to the paediatric wards of Darwin Hospital, and of a larger number of individuals in the communities, have established that the nephritis was preceded by a streptococcal infection, and a recognised nephritogenic streptococcal strain was isolated from a number of children. The clinical course of the disease was mild in the majority of those affected and none had had serious complications. Serological results indicate the importance of measuring antideoxyribonuclease B levels as well as antistreptolysin O titres when seeking evidence of antecedent streptococcal infection.

摘要

1980年期间,北领地的一些原住民社区爆发了急性肾小球肾炎疫情,数百人受到影响。对达尔文医院儿科病房收治的儿童以及社区中更多个体进行的临床和实验室研究表明,肾炎之前存在链球菌感染,并且从一些儿童身上分离出了一种公认的致肾炎性链球菌菌株。该病的临床病程在大多数患者中较为轻微,无人出现严重并发症。血清学结果表明,在寻找先前链球菌感染的证据时,测量抗脱氧核糖核酸酶B水平以及抗链球菌溶血素O滴度非常重要。

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