In-vitro activity of cefotetan and other cephalosporins against multiresistant strains of Enterobacteriaceae.

The activity of cefotetan against multiresistant strains of Escherichia coli and Klebsiella aerogenes was comparable with that of cefotaxime and ceftazidime, the mean MICs being 0.11 and 0.06 mg/l, respectively. Multiresistant strains of Enterobacter cloacae showed a high level of resistance to cefotetan in common with other cephalosporins such as cefuroxime, cefamandole and cefoxitin, but were sensitive to ceftazidime and cefotaxime.