Daschner F D, Goerke C, Bassler M, Just M
Chemotherapy. 1982;28(5):351-4. doi: 10.1159/000238104.
The in vitro activity of cefotetan against Staphylococcus aureus and gram-negative bacterial strains including nonfermenting species has been compared with that of cefoxitin, cefotaxim, moxalactam, cefoperazone and ceftazidime by use of an agar dilution method. Cefotetan was found to be inactive against Pseudomonas aeruginosa and Acinetobacter species and only moderately active against Staphylococcus aureus, Pseudomonas maltophilia, Pseudomonas cepacia, and Enterobacter cloacae. It was more active than cefoxitin and cefoperazone against Escherichia coli, Klebsiella pneumoniae, and indole-positive Proteus strains.
采用琼脂稀释法，将头孢替坦对金黄色葡萄球菌及革兰氏阴性菌（包括非发酵菌）的体外活性与头孢西丁、头孢噻肟、莫西沙星、头孢哌酮及头孢他啶进行了比较。结果发现，头孢替坦对铜绿假单胞菌和不动杆菌属无活性，对金黄色葡萄球菌、嗜麦芽窄食单胞菌、洋葱伯克霍尔德菌和阴沟肠杆菌仅具有中度活性。在针对大肠杆菌、肺炎克雷伯菌及吲哚阳性变形杆菌菌株方面，头孢替坦的活性比头孢西丁和头孢哌酮更强。
