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氟化亚锡与龈下洗必泰冲洗液对菌斑及慢性牙周炎的控制作用

Stannous fluoride and subgingival chlorhexidine irrigation in the control of plaque and chronic periodontitis.

作者信息

Wieder S G, Newman H N, Strahan J D

出版信息

J Clin Periodontol. 1983 Mar;10(2):172-81. doi: 10.1111/j.1600-051x.1983.tb02205.x.

Abstract

The purpose of this study was to investigate the possible benefits of stannous fluoride dentifrice (SnF2) and once daily chlorhexidine (CH) in the control of chronic periodontitis, following a single course of scaling and root planing. 14 adult patients with pockets 4 mm or deeper received a thorough scaling and root planing, followed by instruction in the irrigation of those pockets with CH. They were given either SnF2-containing or a placebo dentifrice, and a new multituft toothbrush, but no instruction in routine oral hygiene. Plaque Index (PII), Sulcus Bleeding Index (SBI) and pocket depth were recorded prior to scaling on day 0. The same parameters and gingival shrinkage were recorded at weeks 1, 2, 4, 8 and 12. CH irrigation was discontinued at day 28. Both groups showed highly significant improvements in all parameters except gingival shrinkage after 28 days. PII was significantly less at all stages in the SnF2 group. It reached baseline values by day 56 in the placebo and day 84 in the SnF2 group. Periodontitis as assessed by SBI remained reduced significantly below baseline values in both groups at the end of the study. At this time there was no significant difference between the groups as regards SBI. It was concluded that a single course of thorough scaling and root planing followed by once daily subgingival irrigation with CH for 1 month, produced a reduction in periodontitis still apparent 2 months after cessation of irrigation. This regime allows a 3-month interval between oral hygiene visits. SnF2-containing dentifrice had a plaque control effect additional to that produced by the regime but had no effect on periodontitis as assessed by SBI.

摘要

本研究的目的是调查在进行单次龈下刮治和根面平整后,含氟亚锡牙膏(SnF2)和每日一次洗必泰(CH)在控制慢性牙周炎方面可能带来的益处。14名牙周袋深度达4毫米或更深的成年患者接受了全面的龈下刮治和根面平整,随后接受了用CH冲洗牙周袋的指导。他们被给予含SnF2的牙膏或安慰剂牙膏,以及一把新的多束毛牙刷,但未接受常规口腔卫生指导。在第0天进行龈下刮治前记录菌斑指数(PII)、龈沟出血指数(SBI)和牙周袋深度。在第1、2、4、8和12周记录相同参数以及牙龈退缩情况。CH冲洗在第28天停止。28天后,两组除牙龈退缩外的所有参数均有高度显著改善。SnF2组在所有阶段的PII均显著更低。安慰剂组在第56天、SnF2组在第84天达到基线值。在研究结束时,两组经SBI评估的牙周炎仍显著低于基线值。此时,两组在SBI方面无显著差异。得出的结论是,单次全面的龈下刮治和根面平整,随后每日一次用CH进行龈下冲洗1个月,在冲洗停止2个月后牙周炎仍有明显减轻。这种治疗方案允许口腔卫生检查间隔3个月。含SnF2的牙膏除了该治疗方案产生的效果外,还有控制菌斑的作用,但对经SBI评估的牙周炎无影响。

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