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[来自各种造血发育异常患者的造血细胞的琼脂培养物]

[Agar cultures of blood forming cells from patients with various forms of hemopoietic dysplasia].

作者信息

Afanasjew B, Kulibaba T, Lukaschewa T, Smirnowa G, Sabelnia T, Podolzewa E

出版信息

Z Gesamte Inn Med. 1983 Feb 1;38(3):67-71.

PMID:6573822
Abstract

By means of a two-layer agar system the growth-types of blood-forming cells of altogether 47 patients with various forms of the haematopoietic dysplasia were investigated. It could be shown that a hypoplastic and a leukemic growth type as a rule represent a prognostically unfavourable criterion. The probability of a transformation to an acute leukosis is greater in such patients whose blood-forming cells show a leukemic growth in the agar culture. The results of clonization may be used for the differential diagnosis between haematopoietic dysplasia and a number of other diseases. The leukemic growth type was proved in 59% of the patients with haematopoietic dysplasia.

摘要

通过双层琼脂系统,对47例各种造血发育异常形式患者的造血细胞生长类型进行了研究。结果表明,造血发育不全型和白血病型生长类型通常代表预后不良的标准。在琼脂培养中造血细胞呈现白血病型生长的患者中,转化为急性白血病的可能性更大。克隆化结果可用于造血发育异常与其他一些疾病的鉴别诊断。59%的造血发育异常患者被证实为白血病型生长类型。

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