Salisbury P L, Jacoway J R
Oral Surg Oral Med Oral Pathol. 1983 Jul;56(1):48-50. doi: 10.1016/0030-4220(83)90054-3.
Amyloidosis as a complication of multiple myeloma carries with it grave prognostic implications, and the median survival of myeloma patients following a diagnosis of amyloidosis is only 4 months. This article describes a patient who survived 6 years with kappa light chain myeloma, but only 4 months after the development of oral amyloid deposits. Oral amyloidosis may be clinically difficult to distinguish from fibrous, neurogenous, or salivary gland pathosis; however, histologic specimens stained with Congo red have a characteristic "apple green" appearance when examined microscopically with polarized light.
淀粉样变性作为多发性骨髓瘤的一种并发症具有严重的预后意义，骨髓瘤患者在诊断为淀粉样变性后的中位生存期仅为4个月。本文描述了一名患有κ轻链骨髓瘤且存活了6年的患者，但在口腔出现淀粉样沉积物后仅存活了4个月。口腔淀粉样变性在临床上可能难以与纤维性、神经性或唾液腺病变相区分；然而，用刚果红染色的组织学标本在偏振光显微镜下检查时具有特征性的“苹果绿”外观。
