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替马西泮作为催眠药的有效性:对804例睡眠障碍患者的开放性多中心评估。

The effectiveness of temazepam as a hypnotic: an open, multi-centre assessment in 804 patients with sleep disorders.

作者信息

Harry T V, Johnson P A

出版信息

Curr Med Res Opin. 1978;5(6):476-83. doi: 10.1185/03007997809111918.

DOI:10.1185/03007997809111918
PMID:657830
Abstract

An open, multi-centre study was carried out in 804 patients complaining of sleep disorders to assess the effectiveness and acceptance of temazepam as a hypnotic. Patients received between 10 mg and 30 mg (mean 16.4 mg) temazepam each night for a week. Subjective assessments using a self-administered questionnaire were made daily of the quality and quantity of sleep. The results showed that sleep induction was rapid and most patients enjoyed a relatively uninterrupted night's sleep, and awakened feeling refreshed. Patient acceptance was good and there was a low incidence of residual or other adverse effects of treatment.

摘要

一项针对804名主诉睡眠障碍的患者开展的开放性多中心研究,旨在评估替马西泮作为催眠药的有效性和可接受性。患者每晚服用10毫克至30毫克(平均16.4毫克)替马西泮,持续一周。每天使用自行填写的问卷对睡眠质量和时长进行主观评估。结果显示,入睡迅速,大多数患者享受了相对不间断的夜间睡眠,醒来时感觉精神焕发。患者接受度良好,治疗的残留或其他不良反应发生率较低。

相似文献

1
The effectiveness of temazepam as a hypnotic: an open, multi-centre assessment in 804 patients with sleep disorders.替马西泮作为催眠药的有效性:对804例睡眠障碍患者的开放性多中心评估。
Curr Med Res Opin. 1978;5(6):476-83. doi: 10.1185/03007997809111918.
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引用本文的文献

1
Temazepam: a review of its pharmacological properties and therapeutic efficacy as an hypnotic.替马西泮:对其作为催眠药的药理特性和治疗效果的综述。
Drugs. 1981 May;21(5):321-40. doi: 10.2165/00003495-198121050-00001.
2
Hypnotic and residual effects of temazepam in volunteers.替马西泮在志愿者中的催眠及残留效应。
Br J Clin Pharmacol. 1980 Jun;9(6):618-20. doi: 10.1111/j.1365-2125.1980.tb01091.x.
3
Pharmacokinetics of the hypnotic benzodiazepine, temazepam.催眠性苯二氮䓬类药物替马西泮的药代动力学
Br J Clin Pharmacol. 1979;8(1):37S-38S. doi: 10.1111/j.1365-2125.1979.tb00453.x.