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替马西泮(优眠)作为催眠药:一项为期十二周的全科医疗试验。

Temazepam (Euhypnos) as a hypnotic: a twelve-week trial in general practice.

作者信息

Fowler L K

出版信息

J Int Med Res. 1977;5(5):295-6. doi: 10.1177/030006057700500501.

DOI:10.1177/030006057700500501
PMID:913856
Abstract

One hundred and forty-seven patients requiring a hypnotic, took soft gelatine capsules containing 10 mg temazepam (Euhypnos) 10-30 mg at night, for up to twelve weeks. One hundred and thirty-three patients (90-5%) completed twelve weeks on drug. Hypnotic performance was rated Good or Very Good in 90% of their assessments and 93-2% of the assessments recorded no hangover effect. Adverse reactions were occasional headaches and nausea. There were no drug-related accidents. One hundred and forty-two patients (96-6%) said there was no adverse effect on their work. Seven patients who did not complete twelve weeks resumed normal sleep patterns and had no further need for hypnotics.

摘要

147名需要使用催眠药的患者,每晚服用含10毫克替马西泮(优诺思)的软胶囊,剂量为10 - 30毫克,持续长达12周。133名患者(90.5%)完成了为期12周的药物治疗。在他们的评估中,90%的催眠效果被评为良好或非常好,93.2%的评估记录没有宿醉效应。不良反应为偶尔的头痛和恶心。没有与药物相关的事故。142名患者(96.6%)表示对他们的工作没有不良影响。7名未完成12周治疗的患者恢复了正常睡眠模式,不再需要催眠药。

相似文献

1
Temazepam (Euhypnos) as a hypnotic: a twelve-week trial in general practice.替马西泮(优眠)作为催眠药:一项为期十二周的全科医疗试验。
J Int Med Res. 1977;5(5):295-6. doi: 10.1177/030006057700500501.
2
Temazepam (Euhypnos) as a hypnotic: a multicentre trial in general practice.替马西泮(优诺思)作为催眠药:一项全科医疗中的多中心试验。
J Int Med Res. 1977;5(5):297-300. doi: 10.1177/030006057700500502.
3
Post-marketing surveillance of Euhypnos (temazepam): a new hypnotic.优诺思(替马西泮)上市后监测:一种新型催眠药。
J Int Med Res. 1980;8(4):295-9. doi: 10.1177/030006058000800410.
4
Euhypnos Forte (temazepam) for resistant insomnia: a clinical trial.优诺思强效片(替马西泮)治疗难治性失眠:一项临床试验。
J Int Med Res. 1979;7(4):295-301. doi: 10.1177/030006057900700407.
5
The effectiveness of temazepam as a hypnotic: an open, multi-centre assessment in 804 patients with sleep disorders.替马西泮作为催眠药的有效性:对804例睡眠障碍患者的开放性多中心评估。
Curr Med Res Opin. 1978;5(6):476-83. doi: 10.1185/03007997809111918.
6
Nitrazepam and temazepam: a comparative trial of two hypnotics.
J Int Med Res. 1976;4(3):145-51. doi: 10.1177/030006057600400301.
7
Temazepam (Euhypnos) and chlormethiazole: a comparative study in geriatric patients.替马西泮(优诺思)与氯美噻唑:老年患者的一项对比研究。
J Int Med Res. 1978;6(2):121-5. doi: 10.1177/030006057800600209.
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Euhypnos Forte (temazepam) in insomniac patients: a clinical trial in general practice.速眠安(替马西泮)用于失眠患者:一项全科医疗中的临床试验
J Int Med Res. 1979;7(4):290-4. doi: 10.1177/030006057900700406.
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Euhypnos Forte (temazepam) for resistant insomnia: post-marketing surveillance, an interim report.优诺思强力片(替马西泮)用于难治性失眠:上市后监测,中期报告。
J Int Med Res. 1979;7(5):379-82. doi: 10.1177/030006057900700508.
10
Euhypnos forte, high dose temazepam for resistant insomnia: post-marketing surveillance in 10,057 patients unresponsive to conventional hypnotic dosage.优诺思强效型,高剂量替马西泮治疗难治性失眠:对10057例对常规催眠剂量无反应患者的上市后监测
J Int Med Res. 1980;8(6):446-52. doi: 10.1177/030006058000800616.

引用本文的文献

1
Temazepam: a review of its pharmacological properties and therapeutic efficacy as an hypnotic.替马西泮:对其作为催眠药的药理特性和治疗效果的综述。
Drugs. 1981 May;21(5):321-40. doi: 10.2165/00003495-198121050-00001.
2
Psychomotor, pulmonary and exercise responses to sleep medication.对睡眠药物的精神运动、肺部及运动反应。
Br J Clin Pharmacol. 1987 Aug;24(2):191-7. doi: 10.1111/j.1365-2125.1987.tb03161.x.