Lutz P, Joncas J H, Brochu P, Demers J
Arch Fr Pediatr. 1983 Jun-Jul;40(6):495-7.
The authors report the case of a 5 year-old girl who died from primary Epstein-Barr virus infection while in remission from acute lymphoblastic leukemia. There was a diffuse, polymorphic and polyclonal proliferation of B lymphocytes, associated with a strong histiocytic reaction with hemophagocytosis. The role of Epstein-Barr virus was ascertained by the appearance of specific antibodies and the finding of EBNA antigen on liver smear.
作者报告了一名5岁女孩的病例,该女孩在急性淋巴细胞白血病缓解期死于原发性爱泼斯坦-巴尔病毒感染。存在B淋巴细胞的弥漫性、多形性和多克隆增殖,并伴有强烈的组织细胞反应及噬血细胞现象。通过特异性抗体的出现以及在肝脏涂片上发现EBNA抗原确定了爱泼斯坦-巴尔病毒的作用。