Wenzel A, Henriksen J, Melsen B
Am J Orthod. 1983 Nov;84(5):422-6. doi: 10.1016/0002-9416(93)90005-r.
The influence of mouth breathing on craniofacial development has previously been demonstrated. Recent investigations do indicate, however, that head posture also might be related to craniofacial morphology. The aim of the present study was to analyze the effect of a topical steroid spray (Budesonide) on nasal respiratory resistance and head posture in children with asthma and nasal obstruction. Thirty-seven children, 8 to 15 years of age, with bronchial asthma, perennial allergic rhinitis, and subjectively assessed mouth breathing were selected for the study. Rhinomanometric and cephalometric analyses were performed. Head posture was defined as the position of the head relative to the cervical column and to the true vertical. After the first examination the children were randomly allocated to two groups, of which one group was treated intranasally with Budesonide (N = 18) and the other with placebo (N = 19), for a double-blind study. After one month of treatment, there was a statistically significant decrease in nasal resistance (p less than 0.001) and an increased flexing of the head (p less than 0.01) (paired t tests) in the children under active treatment. No significant changes were seen in the placebo group. The results indicate that Budesonide nasal spray is capable of reducing nasal obstruction in allergic children and that a reduced nasal resistance leads to a decrease in craniocervical angulation. The clinical importance of these results is yet to be clarified.
口呼吸对颅面发育的影响此前已得到证实。然而,最近的研究确实表明,头部姿势也可能与颅面形态有关。本研究的目的是分析局部用类固醇喷雾剂(布地奈德)对哮喘合并鼻阻塞儿童鼻呼吸阻力和头部姿势的影响。选取37名8至15岁、患有支气管哮喘、常年性变应性鼻炎且主观评估存在口呼吸的儿童进行研究。进行了鼻阻力测量和头影测量分析。头部姿势定义为头部相对于颈椎和真垂线的位置。首次检查后,将儿童随机分为两组,其中一组采用布地奈德鼻内给药(N = 18),另一组采用安慰剂(N = 19),进行双盲研究。治疗一个月后,积极治疗组儿童的鼻阻力有统计学意义的下降(p < 0.001),头部前屈增加(p < 0.01)(配对t检验)。安慰剂组未见明显变化。结果表明,布地奈德鼻喷雾剂能够减轻变应性儿童的鼻阻塞,鼻阻力降低会导致颅颈角度减小。这些结果的临床重要性尚待阐明。