Takeyama H, Yano K, Ohoshima K, Satake T, Emi N, Sugihara T, Kawashima K
Gan To Kagaku Ryoho. 1983 Nov;10(11):2418-22.
A 79 year old man with a history of myocardial infarction and cerebral infarction was admitted to our hospital in August, 1982. The hematological examination showed anemia and leukopenia (myeloblast 12%), and bone marrow aspiration confirmed the diagnosis of acute myeloblastic leukemia (FAB, M2). Because his general condition was poor, he was treated with small dose of Ara-C (10 mg/m2/12 hr, subcutaneous injections), obtaining complete remission. In cases of acute myeloblastic leukemia in elderly patients where other intensive treatments are contraindicated, it appears to be useful to employ a method of small dose of Ara-C therapy.
一名有心肌梗死和脑梗死病史的79岁男性于1982年8月入住我院。血液学检查显示贫血和白细胞减少（原始粒细胞12%），骨髓穿刺确诊为急性髓系白血病（FAB，M2型）。由于他的一般状况较差，给予小剂量阿糖胞苷治疗（10mg/m²/12小时，皮下注射），获得完全缓解。在老年急性髓系白血病患者中，若其他强化治疗禁忌，采用小剂量阿糖胞苷治疗方法似乎是有效的。
