Okamoto Y, Mori M, Miyazaki A, Oguro T, Inada T
Gan No Rinsho. 1987 Jun;33(6):698-702.
A 79-year-old patient with acute myeloblastic leukemia (M2 type in FAB), who has survived more than 5 years, is reported. She was admitted because of fever and anemia. Her white blood cell count was 6200/mm3 with 58% blasts. Bone marrow aspiration showed a nucleated cell count of 26 X 10(4)/mm with 84% blasts, Complete remission was achieved within one month by DCMP two-step method therapy. She relapsed in the third and fifth years after initial therapy. Because leukemic change is atypical, she was treated with a low dose of Ara-C therapy, resulting in complete remission. In cases of acute myelobastic leukemia in elderly patients, long-term survival is rare. However in this case, follow-up has succeeded for 5 years. This patient is the oldest case of acute myeloblastic leukemia ever reported in Japan.
报告了一名79岁的急性髓性白血病（FAB分型为M2型）患者，其存活时间超过了5年。她因发热和贫血入院。她的白细胞计数为6200/mm³，原始细胞占58%。骨髓穿刺显示有核细胞计数为26×10⁴/mm，原始细胞占84%，通过DCMP两步法治疗在1个月内实现了完全缓解。她在初始治疗后的第三年和第五年复发。由于白血病变化不典型，她接受了小剂量阿糖胞苷治疗，从而实现了完全缓解。在老年急性髓性白血病病例中，长期存活很罕见。然而在该病例中，随访成功进行了5年。该患者是日本有史以来报告的年龄最大的急性髓性白血病病例。
