Anantharaman K
Experientia Suppl. 1983;44:157-70. doi: 10.1007/978-3-0348-6540-1_10.
The effects of restriction of energy and/or protein intake were studied in rats during pregnancy and lactation and in adult mice. Three approaches were employed: sucrose stimulus-induced reduction in the intake of an adequate diet given simultaneously; restriction of intake of a complete food by 30% of ad libitum levels and selective protein or energy restriction of a high protein diet and a non-protein diet. Casein or lactalbumin was the protein source. During lactation the rat's natural food intake regulatory mechanism prevailed over the sucrose stimulus. Restricted intake of the complete food and selective restriction of protein or energy, variably influenced gestational and lactational performance and weight of young at weaning. A distinct regulation in the intake of protein and energy during pregnancy and lactation was observed on selective energy or protein restriction. Restricted feeding of the composite diet starting in the second year of life, to mice previously ad libitum fed a lab chow of constant composition, promoted the highest survival rate.
在大鼠孕期和哺乳期以及成年小鼠中研究了能量和/或蛋白质摄入受限的影响。采用了三种方法：蔗糖刺激诱导同时给予的充足日粮摄入量减少；将完全食物的摄入量限制在自由采食水平的30%，以及对高蛋白日粮和无蛋白日粮进行选择性蛋白质或能量限制。酪蛋白或乳白蛋白作为蛋白质来源。在哺乳期，大鼠天然的食物摄入调节机制胜过蔗糖刺激。完全食物摄入受限以及蛋白质或能量的选择性限制，对妊娠和哺乳性能以及断奶时幼崽的体重产生了不同程度的影响。在选择性能量或蛋白质限制的情况下，观察到孕期和哺乳期蛋白质和能量摄入存在明显调节。从生命的第二年开始，对之前自由采食成分恒定的实验室饲料的小鼠进行复合日粮的限制喂养，可提高存活率。
