Watts A, Paterson R C
Oral Surg Oral Med Oral Pathol. 1983 Nov;56(5):542-8. doi: 10.1016/0030-4220(83)90106-8.
The role of bacterial contamination in the toxicity to the pulp of a number of metallic salts was investigated. These had been tested as pulp-capping agents in previous studies involving 228 exposed rat molars. Material from the previous investigations was stained to demonstrate bacteria. This revealed bacteria in necrotic pulp tissue and/or the cavity-restoration interface in approximately 60% of the specimens. The presence of bacteria appeared to be related to pulpal inflammation, necrosis, and failure of calcific repair.
研究了细菌污染在多种金属盐对牙髓毒性中所起的作用。在之前涉及228颗暴露大鼠磨牙的研究中，这些金属盐已作为盖髓剂进行过测试。对先前调查的材料进行染色以显示细菌。这表明，在大约60%的标本中，坏死牙髓组织和/或洞-修复体界面存在细菌。细菌的存在似乎与牙髓炎症、坏死及钙化修复失败有关。
