使用明尼苏达多项人格调查表（MMPI）量表预测锂盐对抑郁症的治疗反应。

Use of an MMPI scale to predict antidepressant response to lithium.

作者信息

Garvey M J, Johnson R A, Valentine R H, Schuster V

出版信息

Psychiatry Res. 1983 Sep;10(1):17-20. doi: 10.1016/0165-1781(83)90024-0.

Abstract

Previous research has indicated that a subset of Minnesota Multiphasic Personality Inventory (MMPI) items may be able to predict antidepressant treatment response to lithium. Twenty-one patients with major depressive disorder were assigned to treatment with lithium based on this MMPI lithium response scale. Twenty lithium-assigned patients completed the 4-week trial. Sixty percent of these patients showed a 50% reduction in Hamilton depression scores. This response rate is similar to results obtained in studies using no selection criteria in the treatment of depression with lithium.

摘要

先前的研究表明，明尼苏达多相人格调查表（MMPI）中的一部分项目或许能够预测锂盐对抑郁症治疗的反应。根据这个MMPI锂盐反应量表，21名重度抑郁症患者被分配接受锂盐治疗。20名被分配接受锂盐治疗的患者完成了为期4周的试验。这些患者中有60%的人汉密尔顿抑郁量表得分降低了50%。这一反应率与在使用锂盐治疗抑郁症时未采用任何选择标准的研究中所获得的结果相似。