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[2274例唇部表皮样上皮瘤的电离辐射治疗结果]

[Results of ionizing radiation treatment of 2274 epidermoid epitheliomas of the lips].

作者信息

Mazeron J J, Richaud P

出版信息

Rev Stomatol Chir Maxillofac. 1983;84(5):305-6.

PMID:6580716
Abstract

In preparation for the 18th meeting of the European Curietherapy Group, devoted to cancer of the lip, 2 363 cases of lip cancer from 23 European Hospitals were retrospectively analysed. After presentation of these results, several free communications, and a large interdisciplinary panel discussion, a consensus was reached for the management of the primary tumor and the regional lymph nodes. Interstitial implant with iridium 192 wires results in a local recurrence rate which does not excede 3,4%. This method may be considered the treatment of choice for T1 and T2 tumors and many T3 tumors. On the other hand surgery should be used for in situ tumors and very large deeply infiltrating tumors. As the 2% failure rate after routine prophylactic neck dissection does not significantly differ from the 3% failure rate when patients undergo neck dissection only if clinically positive neck nodes develop, patients with T1, T2 tumors and no palpable neck nodes, who can be expected to submit to regular follow-up examination, may be managed conservatively. Patients with clinically positive neck nodes should undergo a neck dissection followed by radiationtherapy.

摘要

为筹备欧洲镭疗法组织关于唇癌的第18次会议,对来自23家欧洲医院的2363例唇癌病例进行了回顾性分析。在展示这些结果、进行了几次自由交流以及进行了一场大型跨学科小组讨论之后,就原发性肿瘤和区域淋巴结的处理达成了共识。使用铱192线进行间质植入导致的局部复发率不超过3.4%。这种方法可被视为T1和T2期肿瘤以及许多T3期肿瘤的首选治疗方法。另一方面,原位肿瘤和非常大的深度浸润性肿瘤应采用手术治疗。由于常规预防性颈清扫术后2%的失败率与仅在临床上出现阳性颈部淋巴结时才进行颈清扫的患者3%的失败率没有显著差异,对于T1、T2期肿瘤且无颈部可触及淋巴结且有望接受定期随访检查的患者,可以进行保守处理。临床上颈部淋巴结阳性的患者应进行颈清扫,然后进行放射治疗。

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