Ekedahl C
Scand J Infect Dis Suppl. 1983;39:56-8.
Most patients with sinusitis are treated by general practitioners. Since these doctors generally do not puncture the maxillary sinus, they can not be certain that the patient has a purulent sinus infection, which is the most important sign for determining whether or not the patient should have an antibiotic. Thus, the doctor has to rely on symptoms that are most characteristic of a purulent sinusitis. The symptoms are described and the bacteria most frequently seen in sinusitis are mentioned (Haemophilus influenzae, Streptococcus pneumoniae and anaerobic bacteria). Treatment of maxillary sinusitis should primarily consist of restoring the normal milieu within the sinus by antral puncture and lavage. Penicillin V is still the first antibiotic drug of choice, because of its effectiveness in vitro and in vivo. In therapeutic failure, aeration of the maxillary sinus is first recommended. Cefaclor, tetracyclines or trimethoprim are recommended in patients allergic to penicillins. The agents are also recommended when beta-lactamase-producing strains of H. influenzae and Branhamella catarrhalis are isolated.
大多数鼻窦炎患者由全科医生治疗。由于这些医生一般不穿刺上颌窦,所以他们无法确定患者是否患有化脓性鼻窦感染,而这是决定患者是否应使用抗生素的最重要体征。因此,医生不得不依赖化脓性鼻窦炎最具特征性的症状。文中描述了这些症状,并提及了鼻窦炎中最常见的细菌(流感嗜血杆菌、肺炎链球菌和厌氧菌)。上颌窦炎的治疗应主要通过鼻窦穿刺和灌洗来恢复鼻窦内的正常环境。青霉素V仍然是首选的抗生素药物,因其在体外和体内均有效。治疗失败时,首先建议对上颌窦进行通气。对青霉素过敏的患者推荐使用头孢克洛、四环素或甲氧苄啶。当分离出产生β-内酰胺酶的流感嗜血杆菌和卡他布兰汉菌菌株时,也推荐使用这些药物。