Khoo S K, Molloy D
Aust N Z J Obstet Gynaecol. 1983 Aug;23(3):155-60. doi: 10.1111/j.1479-828x.1983.tb00566.x.
The beta-subunit of chorionic gonadotrophin (beta HCG) was measured by radioimmunoassay in the serum of 190 consecutive patients admitted to hospital with the suspicion of ectopic pregnancy. The detection limit was set at 1 ng/ml. A urine sample was also taken for pregnancy testing on admission. A positive serum beta HCG result was obtained in 36 patients (19%); pregnancy was confirmed in 32 (ectopic pregnancy 14, abortion 8, continuing normal pregnancy 7, retained products 3), giving a predictive value of 89%. There was poor correlation between serum and urine results. The serum levels were low in patients who subsequently aborted, intermediate in those with ectopic pregnancy and within the normal range in patients in whom the pregnancy continued normally. The high predictive value of the test should identify the patients for further investigation, thus avoiding unnecessary operative procedures and prolonged hospital stay.
采用放射免疫分析法对190例因疑似异位妊娠入院的连续患者血清中的绒毛膜促性腺激素β亚基（β-HCG）进行检测。检测限设定为1纳克/毫升。入院时还采集了一份尿液样本进行妊娠检测。36例患者（19%）血清β-HCG检测结果呈阳性；32例妊娠得到确诊（异位妊娠14例、流产8例、持续正常妊娠7例、残留组织3例），预测值为89%。血清和尿液检测结果之间相关性较差。随后流产的患者血清水平较低，异位妊娠患者血清水平处于中等水平，而妊娠正常持续的患者血清水平在正常范围内。该检测的高预测值应能确定需要进一步检查的患者，从而避免不必要的手术操作和延长住院时间。
