Drize N I, Solov'ev G Ia, Skorikova A S, Donskov S I, Grineva N I
Nauchnye Doki Vyss Shkoly Biol Nauki. 1983(11):51-4.
The human blast cells line L-101 isolated from blood leukocytes of the patient with the cutaneous erythromyeloleukemia in the media with dimethyl-sulfoxide (DMSO) and maintained by permanent cultivation stimulate myeloid differentiation of this cells. The number of differentiated cells depends on DMSO concentration. Maximum of differentiated cells (up to 75%) have exposed on the 6th day of incubation with 0,75% DMSO. The cell line L-101 is a suitable model for investigation of myeloid differentiation.
从皮肤红白血病患者血液白细胞中分离出的人原始细胞系L-101，在含有二甲基亚砜（DMSO）的培养基中培养，并通过连续传代维持培养，它能刺激这些细胞的髓系分化。分化细胞的数量取决于DMSO的浓度。在含有0.75% DMSO的培养基中孵育第6天时，分化细胞的比例最高可达75%。细胞系L-101是研究髓系分化的合适模型。
