Dirksen H, Groth S, Munch E
Eur J Respir Dis Suppl. 1983;130:54-8.
The effect of inhalation of two dose sequences of fenoterol inhalation powder were compared in a double-blind cumulative dose response investigation. Nine patients with stable asthma participated in the study. In dose sequence I, 50 + 50 + 100 + 200 micrograms of fenoterol powder were inhaled and in dose sequence II, 200 + 50 + 50 + 50 micrograms fenoterol inhalation powder. There was no significant difference in the effect on lung function or tremor at any point following the two methods of inhalation.
在一项双盲累积剂量反应研究中,比较了吸入两种剂量序列的非诺特罗吸入粉的效果。9名稳定期哮喘患者参与了该研究。在剂量序列I中,吸入50 + 50 + 100 + 200微克的非诺特罗粉,在剂量序列II中,吸入200 + 50 + 50 + 50微克的非诺特罗吸入粉。两种吸入方法后,在任何时间点对肺功能或震颤的影响均无显著差异。