Boye N P, Kornstad S
Eur J Respir Dis Suppl. 1983;130:9-11.
In the present investigation the effect of fenoterol powder for inhalation has been compared to that of fenoterol spray in 20 adult patients with reversible obstructive lung disease. No difference could be demonstrated between the two forms of the drug in a randomized cross-over study. Neither was it possible to demonstrate any difference between the two preparations following the use of the drug at home over a minimum of four days, with regard to daily PEF registration and symptom scores. Nine of the patients preferred spray, six powder.
在本研究中,对20名患有可逆性阻塞性肺病的成年患者吸入用非诺特罗粉雾剂和非诺特罗喷雾剂的效果进行了比较。在一项随机交叉研究中,未发现两种剂型药物之间存在差异。在至少四天的家庭用药后,就每日峰值呼气流速(PEF)记录和症状评分而言,也无法证明两种制剂之间存在任何差异。9名患者更喜欢喷雾剂,6名更喜欢粉雾剂。