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The site of 25-hydroxycholecalciferol stimulated protein synthesis in the rat kidney.

作者信息

Cochran M

出版信息

Experientia. 1978 Jun 15;34(6):719-20. doi: 10.1007/BF01947279.

Abstract

Autoradiographs of the kidneys of rachitic rats dosed in vivo with 250 pmoles 25-hydroxycholecaliferol (25-OHD3) and 3H-leucine showed increased grain counts in portions of proximal renal tubules. On incubation of kidney slices the synthesis of only 1 cytosol protein was found to be stimulated by the steroid. On disc gel electrophoresis it had the characteristics of renal calcium binding protein.

摘要

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