一种用于测量脑组织小样本中皮克量多巴胺和3,4-二羟基苯乙酸（DOPAC）的放射酶法。
A radioenzymatic method to measure picogram amounts of dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) in small samples of brain tissue.
作者信息
Argiolas A, Fadda F
出版信息
Experientia. 1978 Jun 15;34(6):739-41. doi: 10.1007/BF01947294.
PMID:658286
Abstract
A radioenzymatic method for simultaneous determination of dopamine and DOPAC in small brain areas is described. By using this assay, 250 pg of dopamine and 150 pg of DOPAC can be estimated. The present method has been applied to compare the effect of different psychotropic drugs on the dopamine and DOPAC levels in the caudate nucleus, substantia nigra and medial basal hypothalamus.
摘要
本文描述了一种用于同时测定脑小区域中多巴胺和3,4-二羟基苯乙酸（DOPAC）的放射酶法。通过使用该测定法，可以估算出250皮克的多巴胺和150皮克的3,4-二羟基苯乙酸。本方法已用于比较不同精神药物对尾状核、黑质和内侧基底下丘脑多巴胺和3,4-二羟基苯乙酸水平的影响。
Zotero 插件