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腹主动脉结扎后大鼠骨骼肌中5-羟色胺诱导的代谢和形态学变化

Metabolic and morphologic changes induced by serotonin in skeletal muscle of rats after abdominal aorta ligation.

作者信息

Canal N, Nemni R, Tiby V, Sacchi G, Frattola L

出版信息

J Med. 1983;14(5-6):405-13.

PMID:6583299
Abstract

Myopatic changes observed in muscle of rats after abdominal aorta ligation and/or serotonin injection have been regarded as a suitable model to explore the possibility that vasoactive treatments induce muscular damage similar to human myopathies. In the present study, we investigated the effect of serotonin administration to normal and aorta-ligated rats on cAMP-dependent protein-kinase (PK) and hydrolytic enzymes in skeletal muscle.

摘要

在大鼠腹主动脉结扎和/或注射血清素后,其肌肉中观察到的肌病性变化被视为一种合适的模型,用以探究血管活性治疗是否会诱发与人类肌病相似的肌肉损伤。在本研究中,我们研究了给正常大鼠和主动脉结扎大鼠注射血清素后,其骨骼肌中cAMP依赖性蛋白激酶(PK)和水解酶的变化情况。

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J Med. 1983;14(5-6):405-13.
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