Vachová-Fribová M, Elis J
Farmakol Toksikol. 1978 Mar-Apr;41(2):191-3.
The activity of N-acetyltransferase is shown to significantly rise after administration of theophylline and isoprenaline, but not of propranolol and N-acetylderivate of para-aminosalicylic acid to form during 30 minutes at a constant rate that increases following addition of cyclic AMP to the incubation medium. The capacity of the rat to acetylate paraaminosalicylic acid did not change under the effect of the mentioned agents.
在给予茶碱和异丙肾上腺素后，N - 乙酰转移酶的活性显著升高，但给予普萘洛尔和对氨基水杨酸的N - 乙酰衍生物后则不然。在30分钟内，以恒定速率形成，在向孵育培养基中添加环磷酸腺苷后该速率增加。在上述药物的作用下，大鼠乙酰化对氨基水杨酸的能力未发生变化。
