Sherman D M, Goncharov A G, Shvets E G, Iagniatinskiĭ D Ia
Farmakol Toksikol. 1978 May-Jun;41(3):292-6.
Tests conducted with 48 dogs and 100 rabbits demonstrated that intravenous administration of novocain has a well-marked positive influence in extreme conditions, such as massive blood losses and traumatic shocks. It is shown that in the mechanism of the drug's action particularly important is its capability to increase the cardiac performance, to eliminate spasms of resistive vessels and to contract the blood-carrying vessels of the microcirculatory stream. The final effect, however, is in a great measure dependent upon the initial functional state of the organism (the period of hemorrhagic or traumatic shock) and an early introduction of the drug.
对48只狗和100只兔子进行的试验表明，在诸如大量失血和创伤性休克等极端情况下，静脉注射奴夫卡因有明显的积极作用。结果表明，在该药物的作用机制中，特别重要的是其增强心脏功能、消除阻力血管痉挛以及收缩微循环血流中携带血液的血管的能力。然而，最终效果在很大程度上取决于机体的初始功能状态（出血性或创伤性休克期）以及药物的早期使用。
