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一名难治性急性淋巴细胞白血病患者发生播散性佩特里菌病(阿利什菌病)。

Disseminated petriellidiosis (allescheriasis) in a patient with refractory acute lymphoblastic leukaemia.

作者信息

Shih L Y, Lee N

出版信息

J Clin Pathol. 1984 Jan;37(1):78-82. doi: 10.1136/jcp.37.1.78.

Abstract

A case of disseminated petriellidiosis is presented. This complication occurred in a patient with refractory acute lymphoblastic leukaemia, who was receiving repeated courses of cytotoxic drugs, antibiotics and prolonged corticosteroid therapy. The diagnosis of infection by Petriellidium boydii was established by pathological and microbiological studies of a specimen obtained at open lung biopsy. The portal of entry was probably through the lung spreading later via the blood stream to the brain, thyroid and kidneys. The present case once again emphasises the importance of specific microbiological identification in definitive diagnosis. To our knowledge, only three cases of disseminated petriellidiosis have been reported and this case appears to be the first case with renal involvement.

摘要

本文报告1例播散性佩特里菌病。该并发症发生在1例难治性急性淋巴细胞白血病患者中,该患者正在接受反复的细胞毒性药物、抗生素治疗及长期的皮质类固醇治疗。通过对开胸肺活检获取的标本进行病理和微生物学研究,确诊为博伊德氏佩特里菌感染。感染途径可能是经肺进入,随后通过血流扩散至脑、甲状腺和肾脏。本病例再次强调了特异性微生物鉴定在明确诊断中的重要性。据我们所知,仅报告过3例播散性佩特里菌病,而该病例似乎是首例累及肾脏的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/687f/498623/5dd4db360568/jclinpath00172-0088-a.jpg

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