Verhoeven J W
Oral Surg Oral Med Oral Pathol. 1984 Mar;57(3):323-37. doi: 10.1016/0030-4220(84)90190-7.
Contrast media used for sialography were originally developed for other medical applications. Therefore, it was considered desirable to investigate the properties of these substances for use in sialography. Eleven radiopaque substances were selected, and their properties for sialography were studied. An in vitro study was made to determine their contrast qualities and their rate of evacuation after the sialographic examination. In animal experiments the possible harmful effects of the media on salivary gland tissues were studied. Moreover, the effects of the radiopaque material on the extraglandular tissues--which are important in understanding the consequences of spilling into these tissues--were investigated. The results of this study were compared with data from the literature. Conray 80, Amipaque 440, Lipiodol UF, Myodil, and Duroliopaque appear to be the media most suited for sialography, provided glandular overfilling is avoided. A prolonged clinical study is advised for a further selection from these agents.
用于涎腺造影的造影剂最初是为其他医学应用而开发的。因此，研究这些物质用于涎腺造影的特性被认为是可取的。选择了11种不透射线的物质，并研究了它们用于涎腺造影的特性。进行了一项体外研究，以确定它们的造影质量以及涎腺造影检查后的排空率。在动物实验中，研究了造影剂对唾液腺组织可能的有害影响。此外，还研究了不透射线材料对腺外组织的影响——这对于理解造影剂溢入这些组织的后果很重要。将本研究结果与文献数据进行了比较。如果避免腺体过度充盈，Conray 80、Amipaque 440、超液化碘油、Myodil和Duroliopaque似乎是最适合涎腺造影的造影剂。建议进行长期临床研究，以便从这些制剂中进一步筛选。
