Rapid quantitative determination of seven anthracyclines and their hydroxy metabolites in body fluids.
作者信息
Oosterbaan M J, Dirks R J, Vree T B, van der Kleijn E
出版信息
J Chromatogr. 1984 Mar 9;306:323-32. doi: 10.1016/s0378-4347(00)80894-4.
PMID:6585367
Abstract
A reversed-phase high-performance liquid chromatographic method is described for the determination of seven anthracycline analogues and their hydroxy metabolites. The method is suitable for analysis of 30 plasma samples a day. The detection limit is 0.5 ng/ml for all compounds. Examples of the pharmacokinetics of adriamycin and carminomycin in man are shown.
摘要
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