Maruyama T, Hasegawa T, Kobayashi F, Tanaka S, Uda H
J Leukoc Biol. 1984 May;35(5):441-7. doi: 10.1002/jlb.35.5.441.
Cervical and axillary lymph nodes of athymic nude mice were compared morphometrically and ultrastructurally with those of normal littermates. The lymph nodes of the nude mice were larger and the volumes of the follicle, paracortex, and medulla of the lymph nodes were all larger. The paracortex of nude mice had few lymphocytes and a large number of interdigitating cells (IDC) and Langerhans cells (Lc). The results suggest that the high incidence of Lc and IDC in the lymph nodes of nude mice is due to cell accumulation and not lymphocyte depletion.
对无胸腺裸鼠的颈部和腋窝淋巴结与正常同窝小鼠的淋巴结进行了形态计量学和超微结构比较。裸鼠的淋巴结更大，淋巴结的滤泡、副皮质和髓质体积均更大。裸鼠的副皮质区淋巴细胞较少，有大量的交错突细胞（IDC）和朗格汉斯细胞（Lc）。结果表明，裸鼠淋巴结中Lc和IDC的高发生率是由于细胞积聚而非淋巴细胞耗竭所致。
