Hietanen J, Salo O P, Kanerva L, Juvakoski T
Scand J Dent Res. 1984 Feb;92(1):50-4. doi: 10.1111/j.1600-0722.1984.tb00859.x.
The oral cavities of 200 consecutive psoriasis patients, most of them with widespread disease on the skin, were examined (man/woman ratio 1.63:1, mean age of the patients 43.7 yr). The average duration of the disease at time of examination was 15.8 yr. When questioned, 16% of the patients reported changes in the joints, which, according to them, had been verified by radiography. 72.5% of the patients reported on nail involvement at some time during their disease. Fissured tongue was present in 9.5% of the patients, and geographic tongue and smooth tongue each in 1% of the patients. Angular cheilitis was found in 3.5% of the patients. In 20 out of 200 cases, the oral mucosa showed changes and biopsy was taken. Four out of 20 patients showed histologic features typical of psoriasis, including accumulations of leukocytes in the upper layers of the epithelium, all with widespread psoriasis skin involvement. Areas of oral mucosa were most often deep red in color, the buccal mucosa and tongue being the two most common sites. Two out of these four patients had a fissured tongue and one had a geographic tongue.
对200例连续性银屑病患者的口腔进行了检查，其中大多数患者皮肤病变广泛（男女比例为1.63:1，患者平均年龄43.7岁）。检查时疾病的平均病程为15.8年。当被询问时，16%的患者报告有关节变化，据他们称这些变化已通过X线摄影得到证实。72.5%的患者报告在病程中的某个时候有指甲受累情况。9.5%的患者有沟纹舌，1%的患者有地图舌和平滑舌。3.5%的患者有口角炎。在200例病例中的20例中，口腔黏膜出现变化并进行了活检。20例患者中有4例表现出银屑病典型的组织学特征，包括上皮上层白细胞聚集，所有这些患者皮肤均有广泛的银屑病病变。口腔黏膜区域最常呈深红色，颊黏膜和舌是两个最常见的部位。这4例患者中有2例有沟纹舌，1例有地图舌。
