银屑病中的舌部病变：一项对照研究。
Tongue lesions in psoriasis: a controlled study.
作者信息
Daneshpazhooh Maryam, Moslehi Homayoon, Akhyani Maryam, Etesami Marjan
机构信息
Department of Dermatology, Tehran University of Medical Sciences, RAZI Hospital, Vahdate-Eslami Sq, 11966 Tehran, Iran.
出版信息
BMC Dermatol. 2004 Nov 4;4(1):16. doi: 10.1186/1471-5945-4-16.
BACKGROUND
Our objective was to study tongue lesions and their significance in psoriatic patients.
METHODS
The oral mucosa was examined in 200 psoriatic patients presenting to Razi Hospital in Tehran, Iran, and 200 matched controls.
RESULTS
Fissured tongue (FT) and benign migratory glossitis (BMG) were the two most frequent findings. FT was seen more frequently in psoriatic patients (n = 66, 33%) than the control group (n = 19, 9.5%) [odds ratio (OR): 4.69; 95% confidence interval (CI): 2.61-8.52] (p-value < 0.0001). BMG, too, was significantly more frequent in psoriatic patients (28 cases, 14%) than the control group (12 cases, 6%) (OR: 2.55; 95% CI: 1.20-5.50) (p-value < 0.012). In 11 patients (5.5%), FT and BMG coexisted. FT was more frequent in pustular psoriasis (7 cases, 53.8%) than erythemato-squamous types (56 cases, 30.4%). On the other hand, the frequency of BMG increased with the severity of psoriasis in plaque-type psoriasis assessed by psoriasis area and severity index (PASI) score.
CONCLUSIONS
Nonspecific tongue lesions are frequently observed in psoriasis. Further studies are recommended to substantiate the clinical significance of these seemingly nonspecific findings in suspected psoriatic cases.
背景
我们的目的是研究银屑病患者的舌部病变及其意义。
方法
对伊朗德黑兰拉齐医院的200例银屑病患者和200例匹配的对照者进行口腔黏膜检查。
结果
裂纹舌（FT）和良性游走性舌炎（BMG）是最常见的两种表现。银屑病患者中FT的发生率（n = 66，33%）高于对照组（n = 19，9.5%）[比值比（OR）：4.69；95%置信区间（CI）：2.61 - 8.52]（p值<0.0001）。BMG在银屑病患者中也明显更常见（28例，14%），高于对照组（12例，6%）（OR：2.55；95% CI：1.20 - 5.50）（p值<0.012）。11例患者（5.5%）同时存在FT和BMG。脓疱型银屑病中FT更常见（7例，53.8%），高于红斑鳞屑型（56例，30.4%）。另一方面，根据银屑病面积和严重程度指数（PASI）评分评估，在斑块型银屑病中，BMG的发生率随银屑病严重程度增加。
结论
银屑病患者中经常观察到非特异性舌部病变。建议进一步研究以证实这些看似非特异性的发现在疑似银屑病病例中的临床意义。
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