Davies D S
Eur J Respir Dis Suppl. 1984;134:111-7.
The systemic availability of oral terbutaline is limited by incomplete absorption and pre-systemic metabolism in the intestinal wall and/or the liver. There is considerable inter-subject variation in absorption but not in pre-systemic metabolism. Terbutaline is eliminated unchanged or as a conjugate and the degree of conjugation depends on the route of administration.
口服特布他林的全身可用性受到肠道壁和/或肝脏中吸收不完全及首过代谢的限制。吸收方面存在相当大的个体间差异，但首过代谢不存在个体间差异。特布他林以原形或结合物形式被消除，结合程度取决于给药途径。
