Weise W, Bernoth E, Quent P, Weise G
Zentralbl Gynakol. 1977;99(1):29-36.
68 patients were transfered to the prenatal diagnosis. Both the alpa-fetorotein-estimation and the fetography or amniography were performed in 13 patients. The indication for fetography is the exclusion of neural tube defects and other serious visible defects. The amniography can especially carried out in the prenatal diagnosis of defects of intestinal tract. A program is proposed to the prenatal detection of neural tube defects: 1. Examination of all of the pregnacies with ultra sonic B scan. 2. At suspicions ultra sonic B scan and after birth of a child with neural tube defect alpha-fetoproteinestimation at the 16th week of pregnancy and fetography at the 24th week of pregnancy.
68例患者被转诊至产前诊断科室。13例患者同时进行了甲胎蛋白测定及胎儿造影或羊膜造影。胎儿造影的指征是排除神经管缺陷和其他严重的可见缺陷。羊膜造影尤其可用于肠道缺陷的产前诊断。提出了一个神经管缺陷产前检测方案：1. 对所有妊娠进行超声B超检查。2. 超声B超检查有可疑情况时，以及分娩出神经管缺陷患儿后，在妊娠第16周进行甲胎蛋白测定，在妊娠第24周进行胎儿造影。
