用于凝血因子X的新型显色肽底物。
New chromogenic peptide substrates for factor X.
作者信息
Aurell L, Simonsson R, Arielly S, Karlsson G, Friberger P, Claeson G
出版信息
Haemostasis. 1978;7(2-3):92-4. doi: 10.1159/000214241.
PMID:658782
Abstract
The factor Xa-sensitive substrate BZ-Ile-Glu-Gly-Arg-p-nitroanilide has been made more sensitive by making ester and amide derivatives of the gamma-carboxyl group of the glutamyl residue. The morpholinyl and piperidyl amides react 2.5 times more rapidly with factor Xa.
摘要
通过制备谷氨酰残基γ-羧基的酯和酰胺衍生物，凝血因子Xa敏感底物BZ-Ile-Glu-Gly-Arg-对硝基苯胺的敏感性得到了提高。吗啉基和哌啶基酰胺与凝血因子Xa的反应速度快2.5倍。
Zotero 插件