Takuma S, Sawada T, Yama S, Yanagisawa T
J Dent Res. 1984 Sep;63(9):1108-15. doi: 10.1177/00220345840630090201.
Cytological changes in the cementoblasts of rats treated with vincristine were investigated. Accumulation of secretion granules indicated a disturbed secretory mechanism in the cells. Conspicuous dilation of the endoplasmic reticulum suggested disturbance in the transport of substances from the rough endoplasmic reticulum to the Golgi elements. These disturbances were interpreted to be a result of disruption of microtubules.
研究了用长春新碱处理的大鼠成牙骨质细胞的细胞学变化。分泌颗粒的积累表明细胞的分泌机制受到干扰。内质网的明显扩张提示从粗面内质网到高尔基体成分的物质运输受到干扰。这些干扰被解释为微管破坏的结果。
