Poore M, Snow P, Paul C
N Z Med J. 1984 Jun 13;97(757):351-4.
An apparent epidemic of undiagnosed illness in a rural general practice was investigated. The aims were to describe the illness, the characteristics of the people affected, and to look for possible causes. The patients were questioned about their symptoms, and both patients and controls matched for age and sex, were questioned about possible aetiological factors. Twenty-eight cases were identified; all but three were less than 45 years of age; there were equal numbers of females and males. The most commonly experienced symptoms were tiredness, mood and sleep disturbances, headache, and joint or muscle pains. Results of the case-control study suggested that pollution of the water supply, zoonotic infections, contact with agricultural chemicals, and self-dosing with selenium were unlikely to be causes of this illness. An unidentified virus was regarded as the most likely cause.
对某乡村全科医疗中一种未确诊疾病的明显流行情况进行了调查。目的是描述该疾病、受影响人群的特征，并寻找可能的病因。询问了患者的症状，还询问了年龄和性别匹配的患者及对照关于可能的病因因素。共识别出28例病例；除3例以外，所有病例年龄均小于45岁；男女数量相等。最常出现的症状是疲劳、情绪和睡眠障碍、头痛以及关节或肌肉疼痛。病例对照研究结果表明，供水污染、人畜共患感染、接触农用化学品以及自行服用硒不太可能是该疾病的病因。一种未识别的病毒被认为是最可能的病因。
